Since 1996, scientific researchers and doctors in clinical practice have been studying the effects of EMPowerplus on mental disorders such as bipolar disorder. Results have been very encouraging and significant.

Dr. Bonnie Kaplan, a respected behavioral research scientist and one of the principal researchers on several of the published studies says, “If substantiated in controlled trials, the normalization of the mentally ill via nutrient supplementation would be the most significant breakthrough in the field of mental illness since the beginning of time.”

Additional studies by qualified researchers are currently underway, with others in the planning stages.


Successful Treatment of Bipolar Disorder II and ADHD with a Micronutrient Formula: A Case Study.
Rucklidge JJ, Harrison R.
CNS Spectrums. 2010 May;15(5):289-95.

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Micronutrients versus standard medication management in autism: a naturalistic case-control study.
Mehl-Madrona L, Leung B, Kennedy C, Paul S, Kaplan BJ.
Journal of Child and Adolescent Psychopharmacology. 2010 Apr;20(2):95-103.

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Effect of micronutrients on behavior and mood in adults with ADHD: evidence from an 8-week open label trial with natural extension.
Rucklidge J, Taylor M, Whitehead K.
Journal of Attention Disorders. 2010 Jan 13. (Epub ahead of print).

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Successful treatment of OCD with a micronutrient formula following partial response to Cognitive Behavioral Therapy (CBT): a case study.
Rucklidge JJ.
Journal of Anxiety Disorders. 2009 Aug;23(6):836-40.

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Multinutrient supplement as treatment: literature review and case report of a 12-year-old boy with bipolar disorder.
Frazier EA, Fristad MA, Arnold LE.
Journal of Child and Adolescent Psychopharmacology. 2009 Aug;19(4):453-60.

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Database analysis of adults with bipolar disorder consuming a micronutrient formula.
Gately D, Kaplan BJ.
Clinical Medicine Insights: Psychiatry. 2009 Apr;4:3-16. (2009).

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Improved mood and behavior during treatment with a mineral-vitamin supplement: an open-label case series of children.
Kaplan BJ, Fisher JE, Crawford SG, Field CJ, Kolb B.
Journal of Child and Adolescent Psychopharmacology. 2004 Spring;14(1):115-22.

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Nutritional approach to bipolar disorder.
Simmons M.
Journal of Clinical Psychiatry. 2003 Mar;64(3):338.

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Treatment of mood lability and explosive rage with minerals and vitamins: two case studies in children.
Kaplan BJ, Crawford SG, Gardner B, Farrelly G.
J Child Adolesc Psychopharmacol. 2002 Fall;12(3):205-19.

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Effective mood stabilization with a chelated mineral supplement: an open-label trial in bipolar disorder.
Kaplan BJ, Simpson JS, Ferre RC, Gorman CP, McMullen DM, Crawford SG.
Journal of Clinical Psychiatry. 2001 Dec;62(12):936-44.

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Do vitamins or minerals (apart from lithium) have mood-stabilizing effects?
Popper CW.
Journal of Clinical Psychiatry. 2001 Dec;62(12):933-5.

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