EMPowerplus™ Studies

Dr. Bonnie Kaplan, a respected behavioral research scientist and one of the principal researchers on several of the published studies says, “If substantiated in controlled trials, the normalization of the mentally ill via nutrient supplementation would be the most significant breakthrough in the field of mental illness since the beginning of time.”
Additional studies by qualified researchers are currently underway, with others in the planning stages.
Micronutrients reduce stress and anxiety following a 7.1 earthquake in adults with Attention-Deficit/Hyperactivity Disorder.
Rucklidge J, Johnstone J, Harrison R, Boggis A.
Psychiatry Research. 2011 Jul 28. [Epub ahead of print]
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Rucklidge J, Johnstone J, Harrison R, Boggis A.
Psychiatry Research. 2011 Jul 28. [Epub ahead of print]
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Systematic review of safety and tolerability of a complex micronutrient formula used in mental health.
Simpson JS, Crawford SG, Goldstein ET, Field C, Burgess E, Kaplan BJ.
BMC Psychiatry. 2011 Apr 18;11:62.
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Simpson JS, Crawford SG, Goldstein ET, Field C, Burgess E, Kaplan BJ.
BMC Psychiatry. 2011 Apr 18;11:62.
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Database analysis of children and adolescents with bipolar disorder consuming a micronutrient formula.
Rucklidge JJ, Gately D, Kaplan BJ.
BMC Psychiatry. 2010 Sep 28;10:74.
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Rucklidge JJ, Gately D, Kaplan BJ.
BMC Psychiatry. 2010 Sep 28;10:74.
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Successful Treatment of Bipolar Disorder II and ADHD with a Micronutrient Formula: A Case Study.
Rucklidge JJ, Harrison R.
CNS Spectrums. 2010 May;15(5):289-95.
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Rucklidge JJ, Harrison R.
CNS Spectrums. 2010 May;15(5):289-95.
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Micronutrients versus standard medication management in autism: a naturalistic case-control study.
Mehl-Madrona L, Leung B, Kennedy C, Paul S, Kaplan BJ.
Journal of Child and Adolescent Psychopharmacology. 2010 Apr;20(2):95-103.
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Mehl-Madrona L, Leung B, Kennedy C, Paul S, Kaplan BJ.
Journal of Child and Adolescent Psychopharmacology. 2010 Apr;20(2):95-103.
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Effect of micronutrients on behavior and mood in adults with ADHD: evidence from an 8-week open label trial with natural extension.
Rucklidge J, Taylor M, Whitehead K.
Journal of Attention Disorders. 2011 Jan;15(1):79-91.
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Rucklidge J, Taylor M, Whitehead K.
Journal of Attention Disorders. 2011 Jan;15(1):79-91.
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Successful treatment of OCD with a micronutrient formula following partial response to Cognitive Behavioral Therapy (CBT): a case study.
Rucklidge JJ.
Journal of Anxiety Disorders. 2009 Aug;23(6):836-40.
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Rucklidge JJ.
Journal of Anxiety Disorders. 2009 Aug;23(6):836-40.
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Multinutrient supplement as treatment: literature review and case report of a 12-year-old boy with bipolar disorder.
Frazier EA, Fristad MA, Arnold LE.
Journal of Child and Adolescent Psychopharmacology. 2009 Aug;19(4):453-60.
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Frazier EA, Fristad MA, Arnold LE.
Journal of Child and Adolescent Psychopharmacology. 2009 Aug;19(4):453-60.
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Database analysis of adults with bipolar disorder consuming a micronutrient formula.
Gately D, Kaplan BJ.
Clinical Medicine Insights: Psychiatry. 2009 Apr;4:3-16. (2009).
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Gately D, Kaplan BJ.
Clinical Medicine Insights: Psychiatry. 2009 Apr;4:3-16. (2009).
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Improved mood and behavior during treatment with a mineral-vitamin supplement: an open-label case series of children.
Kaplan BJ, Fisher JE, Crawford SG, Field CJ, Kolb B.
Journal of Child and Adolescent Psychopharmacology. 2004 Spring;14(1):115-22.
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Kaplan BJ, Fisher JE, Crawford SG, Field CJ, Kolb B.
Journal of Child and Adolescent Psychopharmacology. 2004 Spring;14(1):115-22.
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Nutritional approach to bipolar disorder.
Simmons M.
Journal of Clinical Psychiatry. 2003 Mar;64(3):338.
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Simmons M.
Journal of Clinical Psychiatry. 2003 Mar;64(3):338.
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Treatment of mood lability and explosive rage with minerals and vitamins: two case studies in children.
Kaplan BJ, Crawford SG, Gardner B, Farrelly G.
Journal of Child and Adolescent Psychopharmacology. 2002 Fall;12(3):205-19.
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Kaplan BJ, Crawford SG, Gardner B, Farrelly G.
Journal of Child and Adolescent Psychopharmacology. 2002 Fall;12(3):205-19.
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Do vitamins or minerals (apart from lithium) have mood-stabilizing effects?
Popper CW.
Journal of Clinical Psychiatry. 2001 Dec;62(12):933-5.
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Popper CW.
Journal of Clinical Psychiatry. 2001 Dec;62(12):933-5.
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Effective mood stabilization with a chelated mineral supplement: an open-label trial in bipolar disorder.
Kaplan BJ, Simpson JS, Ferre RC, Gorman CP, McMullen DM, Crawford SG.
Journal of Clinical Psychiatry. 2001 Dec;62(12):936-44.
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Kaplan BJ, Simpson JS, Ferre RC, Gorman CP, McMullen DM, Crawford SG.
Journal of Clinical Psychiatry. 2001 Dec;62(12):936-44.
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